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By Mary Phipps, Malcolm Quine

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1999). On dependence estimation using correlated failure time data from case–control family studies. Biometrika 86, 743–753. Y. (2000). Cox regression with accurate covariate unascertainable: A nonparametric correction approach. Journal of the American Statistical Association 45, 1209–1219. A. (2005). Why most published findings are false. PLoS Medicine 2(8), e124. , Women’s Health Initiative Investigators. (2006). Calcium plus vitamin D supplementation and the risk of fractures. The New England Journal of Medicine 354, 669–683.

Johns Hopkins University Press, Baltimore, MD. S. (2003). The Statistical Evaluation of Medical Tests for Classification and Production. Oxford University Press, London. R. (1991). A nonparametric method for dealing with mis-measured covariate data. Journal of the American Statistical Association 86, 108–113. L. (1986). A case–cohort design for epidemiologic cohort studies and disease prevention trials. Biometrika 73, 1–11. L. (1989). Surrogate endpoints in clinical trials: Discussion, definition and operational criteria.

Gower, who filled the wrong prescription and was convicted of manslaughter because George was not there to catch the error as he did in the actual world. The causal effect of George not being born is the comparison of (a) the entire stream of events in the actual world with him in it, to (b) the entire stream of events in the counterfactual world without him in it. Fortunately for George, he has Clarence to show him both potential outcomes, and George regrets ever having wished he had never been born, and he returns to the actual world.

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